Table 1.
Demographic and echocardiographic data of the IPF and control groups at rest.
| Variable | IPF∗ (n = 20) | Control (n = 10) | 95% CI of difference | P |
| Age (year) | 72.3 ± 8.6 | 68.5 ± 5.2 | −9.8 to 2.3 | .219 |
| Sex (Female/male) | 10/10 | 6/4 | .619 | |
| BMI (Kg/m2) | 24.7 ± 3.4 | 25.3 ± 2.4 | −2.3 to 3.5 | .668 |
| SBP (mmHg) | 139.0 ± 23.3 | 124.0 ± 15.0 | −34.5 to 4.5 | .127 |
| DBP (mmHg) | 82.0 ± 10.0 | 76.5 ± 10.7 | −14.6 to 3.8 | .238 |
| SpO2 rest (%) | 93.2 ± 1.6 | 94.1 ± 1.4 | −0.03 to 2.43 | .056 |
| FVC% | 67.1 ± 15.2 | – | – | |
| FEV1% | 74.3 ± 11.7 | – | – | |
| DLCO% | 53.9 ± 19.0 | – | – | |
| LA (mL/m2) | 20.8 ± 6.2 | 14.7 ± 4.4 | −10.5 to −1.4 | .011 |
| RA (mL/m2) | 15.5 ± 5.8 | 12.5 ± 5.6 | −7.5 to 1.6 | .199 |
| RV FAC (%) | 46.8 ± 9.9 | 62.0 ± 7.6 | 7.8 to 22.4 | <.001 |
| RV TAPSE (mm) | 20 ± 3 | 22 ± 2 | 0.4 to 5.1 | .012 |
| TDI RV Sm peak (cm/s) | 12 ± 2 | 13 ± 2 | 1.0 to 1.6 | .695 |
| sPAP (mmHg) | 33.4 ± 10.8 | 22.8 ± 7.1 | −18.4 to −2.8 | .009 |
| mPAP (mmHg) | 21.8 ± 6.2 | 15.4 ± 4.5 | −10.9 to −1.7 | .008 |
| E/E′ average | 7.7 ± 1.9 | 7.2 ± 1.3 | −1.9 to 0.8 | .458 |
BMI = body mass index, DBP = diastolic blood pressure, DLCO% = carbon monoxide diffusing capacity of the lung, E/E′ = mitral E/E′ ratio, FEV1% = forced expiratory volume in 1 s as a percentage of the predicted value, FVC% = forced vital capacity as a percentage of the predicted value, IPF = idiopathic pulmonary fibrosis, LA = left atrium, mPAP = mean PA pressure, RA = right atrium, RV FAC = right ventricle fractional area change, SBP = systolic blood pressure, sPAP = systolic PA pressure, SpO2 = peripheral oxyhemoglobin saturation, TAPSE = tricuspid annular plane systolic excursion, TDI RV Sm peak = tissue Doppler imaging of lateral tricuspid systolic annulus velocity
Data are presented as the mean ± standard deviation.