FIG. 2.

Engineered in vitro human skin equivalents. (a) Schematic and pictures of a dermo-epidermal human skin equivalent (HSE) cultured in a transwell insert. Images are kindly provided by Cristina Quílez from our group. (b) Epidermal skin equivalent at 7 and 28 days of culture at the air-liquid interface, scale bars: 100 μm. (c) Dermo-epidermal skin equivalent at 7 and 28 days of culture at the air-liquid interface, scale bars: 30 μm. (b) and (c) are modified images. Reprinted with permission from Roger et al., J. Anat. 234, 4 (2019). Copyright 2019 Authors, licensed under a Creative Commons Attribution (CCBY) License 4.0.²³