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. 2021 Jun 22;5(12):2650–2659. doi: 10.1182/bloodadvances.2021004192

Table 1.

Demographics, disease, and transplant characteristics

Variable N (%) or median (range)
RIC (n = 19) MAC (n = 19) All (n = 38)
Sex
 Female 8 (42) 11 (58) 19 (50)
 Male 11 (58) 8 (42) 19 (50)
Race
 White 12 (63) 12 (63) 24 (63)
 Asian 4 (21) 4 (21) 8 (21)
 Black 2 (11) 2 (11) 4 (11)
 Unknown 1 (5) 1 (5) 2 (5)
Ethnicity
 Hispanic 3 (16) 8 (42) 11 (29)
 Non-Hispanic 15 (79) 11 (58) 26 (68)
 Unknown 1 (5) 0 (0) 1 (3)
Patient’s age at HCT (y) 63 (33-72) 44 (21-57) 53 (21-72)
Primary disease
 AML 5 (26) 12 (64) 17 (45)
 ALL 3 (16) 5 (26) 8 (21)
 MDS 5 (26) 1 (5) 6 (16)
 NHL 3 (16) 0 (0) 3 (8)
 CML 2 (11) 1 (5) 3 (8)
 CLL 1 (5) 0 (0) 1 (2)
HCT comorbidity index 3 (0-6) 2 (0-6) 2 (0-6)
 0 1 (5) 5 (26) 6 (16)
 1-2 8 (42) 7 (37) 15 (39)
 >2 10 (53) 7 (37) 17 (45)
DRI
 Low 3 (16) 0 (0) 3 (8)
 Intermediate 8 (42) 14 (74) 22 (58)
 High 5 (26) 5 (26) 10 (26)
 Very high 3 (16) 0 (0) 3 (8)
Sex donor/recipient
 Female/male 4 (21) 0 (0) 4 (11)
 Others 15 (79) 19 (100) 34 (89)
Donor age at HCT (y) 35 (24-53) 29 (19-48) 32 (19-53)
Patient CMV status
 Negative 3 (16) 5 (26) 8 (21)
 Positive 16 (84) 14 (74) 30 (79)
CD34+ dose (106 cells/kg) 5.28 (2.39-9.35) 6.28 (3.53-9.04) 5.45 (2.39-9.35)
Number of mismatches 3 (1-4) 2 (1-4) 2 (1-4)
HLA class I (A B C)
 Matched 3 (16) 2 (11) 5 (13)
 Mismatched (≥1) 16 (84) 17 (89) 33 (87)
HLA class II (DR DQ DP)
 Matched 3 (16) 5 (26) 8 (21)
 Mismatched (≥1) 16 (84) 14 (74) 30 (79)
HLA DQ
 Matched 18 (95) 18 (95) 36 (95)
 Mismatched (≥1) 1 (5) 1 (5) 2 (5)
HLA DP
 Matched 4 (21) 6 (32) 10 (26)
 Mismatched (≥1) 15 (79) 13 (68) 28 (74)