Table 1.
Variable | N (%) or median (range) | ||
---|---|---|---|
RIC (n = 19) | MAC (n = 19) | All (n = 38) | |
Sex | |||
Female | 8 (42) | 11 (58) | 19 (50) |
Male | 11 (58) | 8 (42) | 19 (50) |
Race | |||
White | 12 (63) | 12 (63) | 24 (63) |
Asian | 4 (21) | 4 (21) | 8 (21) |
Black | 2 (11) | 2 (11) | 4 (11) |
Unknown | 1 (5) | 1 (5) | 2 (5) |
Ethnicity | |||
Hispanic | 3 (16) | 8 (42) | 11 (29) |
Non-Hispanic | 15 (79) | 11 (58) | 26 (68) |
Unknown | 1 (5) | 0 (0) | 1 (3) |
Patient’s age at HCT (y) | 63 (33-72) | 44 (21-57) | 53 (21-72) |
Primary disease | |||
AML | 5 (26) | 12 (64) | 17 (45) |
ALL | 3 (16) | 5 (26) | 8 (21) |
MDS | 5 (26) | 1 (5) | 6 (16) |
NHL | 3 (16) | 0 (0) | 3 (8) |
CML | 2 (11) | 1 (5) | 3 (8) |
CLL | 1 (5) | 0 (0) | 1 (2) |
HCT comorbidity index | 3 (0-6) | 2 (0-6) | 2 (0-6) |
0 | 1 (5) | 5 (26) | 6 (16) |
1-2 | 8 (42) | 7 (37) | 15 (39) |
>2 | 10 (53) | 7 (37) | 17 (45) |
DRI | |||
Low | 3 (16) | 0 (0) | 3 (8) |
Intermediate | 8 (42) | 14 (74) | 22 (58) |
High | 5 (26) | 5 (26) | 10 (26) |
Very high | 3 (16) | 0 (0) | 3 (8) |
Sex donor/recipient | |||
Female/male | 4 (21) | 0 (0) | 4 (11) |
Others | 15 (79) | 19 (100) | 34 (89) |
Donor age at HCT (y) | 35 (24-53) | 29 (19-48) | 32 (19-53) |
Patient CMV status | |||
Negative | 3 (16) | 5 (26) | 8 (21) |
Positive | 16 (84) | 14 (74) | 30 (79) |
CD34+ dose (106 cells/kg) | 5.28 (2.39-9.35) | 6.28 (3.53-9.04) | 5.45 (2.39-9.35) |
Number of mismatches | 3 (1-4) | 2 (1-4) | 2 (1-4) |
HLA class I (A B C) | |||
Matched | 3 (16) | 2 (11) | 5 (13) |
Mismatched (≥1) | 16 (84) | 17 (89) | 33 (87) |
HLA class II (DR DQ DP) | |||
Matched | 3 (16) | 5 (26) | 8 (21) |
Mismatched (≥1) | 16 (84) | 14 (74) | 30 (79) |
HLA DQ | |||
Matched | 18 (95) | 18 (95) | 36 (95) |
Mismatched (≥1) | 1 (5) | 1 (5) | 2 (5) |
HLA DP | |||
Matched | 4 (21) | 6 (32) | 10 (26) |
Mismatched (≥1) | 15 (79) | 13 (68) | 28 (74) |