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. 2021 Jun 11;9:669354. doi: 10.3389/fcell.2021.669354

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Copyright © 2021 Dom, Dmitriev, Lambot, Van Vliet, Glinoer, Libert, Lefort, Dumont and Maenhaut.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overview of transcriptomic analyses. Sample composition of the four transcriptomic datasets used in the study (AT, ET, AM, and EM) and comparisons between them. Comparison 1 (AT vs. ET) addressed changes in gene expression observed in the course of thyroid maturation. Comparison 2 (AT vs. AM) and comparison 4 (ET vs. EM) allowed to reveal transcriptional signatures of adult and embryonic thyroids respectively. Comparison 3 (AM vs. EM) addressed changes in gene expression observed in the course of non-thyroid development. M, male. F, female. Week, gestational week. M, male. F, female. Embryonic thyroids (ET) and Adult thyroids (AT): this study. Embryonic tissues mix (EM): Yi et al. (2010), GSE15744. Adult tissues mix (AM): Tateno et al. (2013), GSE 18674.