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. 2021 Jun 11;9:669354. doi: 10.3389/fcell.2021.669354

TABLE 1B.

Genes specifically enriched in the embryonic thyroids.

Gene symbol Gene description Function
ATP11A ATPase phospholipid transporting 11A – > membrane transporter Transport
BLNK B-cell linker Signaling
CHRNA9 Cholinergic receptor nicotinic alpha 9 subunit Signaling
CYP4 × 1 Cytochrome P450 family 4 subfamily X member 1 Oxidoreductase
FREM3 FRAS1 related extracellular matrix 3 Cytoskeleton/ECM
GCM2 Glial cells missing homolog 2 Gene expression
GPR160 G protein-coupled receptor 160 Signaling
KCNK5 Potassium two pore domain channel subfamily K member 5 Channel
LUZP1 Leucine zipper protein 1
MAP4 Microtubule associated protein 4 Cytoskeleton/ECM
NPFFR2 Neuropeptide FF receptor 2 Signaling
OLFM3 Olfactomedin 3 Cytoskeleton/ECM
PCDH20 Protocadherin 20 Cytoskeleton/ECM
PERP PERP, TP53 apoptosis effector
PSMB8 Proteasome subunit beta 8 Transport
SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
SLC15A2 Solute carrier family 15 member 2 Channel
SLC22A3 Solute carrier family 22 member 3 Channel
TNFRSF11A TNF receptor superfamily member 11a Signaling

Top 20 genes regulated in embryonic thyroids compared to embryonic tissues mix, and not regulated in adult thyroids compared to adult tissues mix.