Table 3.

COVID-19 Vaccine and myocarditis.

Case	Age/Sex	Comorbidities	Echo	ECG	CRP	Trop	Coronary Angio	Symptom	Symptoms onset	cMRI
Albert [29]	24 M	N/A	Normal	Sinus Rhythm	26.4	Trop 18.94	Normal	CP Fever Chills Myalgia	4 d $\overline{p}$ 2nd	T2- Mild myocardial/epicardial delayed gadolinium; Patchy
Mouch 1 [28]	24 M	None	Normal	Diffuse ST elevation	58.1	Trop: 589	NA	CP	3d $\overline{p}$ 2nd	T2- Mild myocardial edema; LGE in subepicardial region
Mouch 2 [28]	20 M	None	LVEF 50–55% Apical Hypokinesia	Sinus tachycardia ST elevation: V2–V6	100	Trop: 1062	Normal	CP	1d $\overline{p}$ 2nd	T2- Mild myocardial edema; LGE in subepicardial region of basal/middle anterolateral and inferolateral walls
Mouch 3 [28]	29 M	Obesity	Normal	Diffuse PR depression/ ST elevation	86	Trop: 876	Normal	CP	2d $\overline{p}$ 2nd	T2- Mild, diffuse myocardial edema; LGE in subepicardial region of the basal inferolateral, anterolateral, and anteroseptal walls
Mouch 4 [28]	45 M	HLD	LVEF 50–55%	ST elevation: I, aVL Inverted T: V3–V5 ST depression: III, aVF	56.2	Trop: 392	Normal	CP	16d $\overline{p}$ 1st	T2- Subepicardial edema of middle anterolateral, inferolateral and apical anterior walls; LGE present in same segments
Mouch 5 [28]	16 M	None	Normal	ST elevation: V2–V4	1.6	Trop: 14350	Normal	CP Myalgia	1d $\overline{p}$ 2nd	T2- Midmyocardial/Subepicardial edema of basal inferolateral and middle anterolateral walls; LGE present in same segments
Mouch 6 [28]	17 M	Obesity	Normal	N/A	54.7	Trop: 1130	NA	CP	3d $\overline{p}$ 2nd	T2- Subepicardial edema of basal/middle inferolateral, inferior-septal, apical anterior & inferior walls; LGE present in same segments; Mid-myocardial enhancement of the middle inferolateral/anterolateral, apical anterior, and lateral walls c/w myopericarditis
García [30]	39 M	Asthma Autoimmune hypothyroidism Chronic atrophic gastritis Atrial fibrillation	Normal	Sinus tachycardia Narrow QRS Diffuse ST-segment	N/A	Trop: 854	NA	CP	6hrs $\overline{p}$ 2nd	T2- Myocardial edema; Subpericardial enhancement of the lateral mediastinal
Ammirati 1 [33]	56 M	N/A	N/A	Minimal ST elevation of Precordial Leads Peaked T waves	2.9	Trop: 515	Normal	N/A	3d $\overline{p}$ 2nd	T2- Subepicardial edema of basal and apical inferolateral walls; Focal subepicardial-intramyocardial (non-ischemic pattern) LGE present in same segments c/w acute myocarditis
Marshall 1 [34]	16 M	N/A	Normal	AV dissociation with junctional escape ST elevation	12.3	Trop: 12.43	Normal	N/A	2d $\overline{p}$2nd	T2- LGE c/w acute myocarditis
Marshall 2 [34]	19 M	N/A	Normal	Sinus tachycardia Diffuse ST elevation	6.7	Trop: 232	Normal	N/A	3d $\overline{p}$ 2nd	T2- mid-wall LGE along basal inferolateral wall segment; Patchy
Marshall 3 [34]	17 M	N/A	Borderline basal lateral/posterior strain	Abnormal T wave Diffuse ST elevation c/w acute pericarditis	2.53	Trop: 5550	Borderline basal lateral/posterior strain	N/A	2d $\overline{p}$ 2nd	T2- LGE of LV subepicardial basal anterolateral and basal to mid-ventricular inferolateral segments c/w myonecrosis
Marshall 4 [34]	18 M	N/A	Normal	ST elevation	12.7	Trop: 1090	Normal	N/A	3d $\overline{p}$ 2nd	T2- Edema, hyperemia, and fibrosis of segments c/w acute myocarditis
Marshall 5 [34]	17 M	N/A	Normal	ST elevation	18.1	Trop: 3200	Normal	N/A	3d $\overline{p}$ 2nd	T2- Subepicardial edema; LGE revealed complete transmural LV free wall
Marshall 6 [34]	16 M	N/A	Normal	ST-elevation	1.8	Trop: 660	Normal	N/A	3d $\overline{p}$ 2nd	T2- Diffuse subepicardial edema; LGE present in same segment
Marshall 7 [34]	14 M	N/A	Mildly depressed LV/RV systolic function	Diffuse ST elevation c/w acute pericarditis	12.7	Trop: 22100	Mildly depressed LV/RV systolic function LVEF 47%	N/A	2d $\overline{p}$ 2nd	T2- Subepicardial edema of middle and apical LV free wall; LGE present in same segments revealed fibrosis.
D'Angelo 1 [32]	30 M	N/A	Preserved EF, mild pericardial effusion, segmental wall motion abnormality of apical portion of interventricular septum	ST elevation: V2–V4, Non-specific T-wave changes: V5 and V6	39.6	Trop: 12546.8	NA	N/A	3d $\overline{p}$ 2nd	T2-weighted STIR- Increased myocardial and pericardial signal intensity
Our Case	70 F	Multiple Sclerosis	LVEF 10% - diffuse LV hypokinesis	sinus tachycardia – inverted T: V4–V6	7.2	Trop 2050	–	Dyspnea	2d J&J	–

CP: chest pain; ECG = Electrocardiogram; CXR: chest x-ray; CTA: computed tomography angiography; Echo: transesophageal echocardiography or transthoracic echocardiography; Peak CRP= Peak C-Reactive Protein, reported in; Peak Trop = Peak Troponin T or I, reported in; TTE = Trans-Thoracic Echocardiogram; cMRI = Cardiac MRI; LGE = Late Gadolinium Enhancement; NA= Not assessed; c/w = Consistent With; $\overline{p}$ = After; J&J: Johnson & Johnson's single-dose COVID-19 vaccine.