Table 2.

HCC imaging systems: similarities and differences in guidelines. Adapted from [41, 43]

Component	American Association for the Study of Liver Diseases	Asian Pacific Association for the Study of the Liver	European Association for the Study of the Liver	Japan Society of Hepatology	Korean Liver Cancer Association-National Cancer Center
“APHE”	Non-rim APHE	APHE	Non-rim APHE	APHE	Non-targetoid APHE
“Washout” on gadoxetic acid–enhanced MRI	PVP only	PVP (and HBP)	PVP only	PVP, HBP	PVP, TP, HBP
CEUS as second modality	No	Yes (Sonazoid)	Yes	Yes (Sonazoid)	Yes
Diagnosis category	LR-1~5, LR-M	HCC	HCC	HCC	HCC, probable HCC, indeterminate
Image criteria for < 1-cm HCC	No	Yes	No	No	No
Capsule as a major criterion	Yes	No	No	No	No
“Interval growth” as a major criterion	Yes	No	No	No	No

Abbreviations: APHE, arterial phase hyperenhancement; CEUS, contrast-enhanced ultrasound; HBP, hepatobiliary phase; HCC, hepatocellular carcinoma; PVP, portovenous phase; TP, transitional phase