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. 2021 May 20;166(8):2305–2310. doi: 10.1007/s00705-021-05092-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Comparative phylogenetic analysis base on complete genome sequences of C. difficile siphoviruses available in the GenBank database. The figure represents the guide tree calculated using the progressive Mauve algorithm. Numbers associated with each branch represent node ages. b Comparison of the genome sequence of phage phiCDKH01 (top) with phiCD24-1 (bottom). Predicted ORFs and the direction of transcription are indicated by block arrows. The blue box represents a putative CRISPR element. Conserved regions are shaded in grey. The colour intensity corresponds to sequence identity level (89% to 100%). Genomic comparisons were performed using BLASTn. Similarities with E values lower than 1e-100 are plotted. The figure was produced using Easyfig 2.2.5 [26].