Fig. 3.

AAV-Rbbp7 into CA1 of the hippocampus does not improve spatial cognition. a The adeno-associated viruses (AAVs) bilaterally injected into CA1 of the hippocampus. [anterior–posterior (AP); medial–lateral (ML); dorsal–ventral (DV)]. b, c Escape latency and distance traveled in the 5-day learning phase of the Morris water maze. d–f Results of the day 6 probe trails of the MWM. g, h Low and high magnification photomicrographs depicting the spread of AAV with the GFP reporter in the hippocampus. Line graphs are means ± SE. Box plots: center line represents the median, the limits represent the 25th and 75th percentile, and the whiskers represent the minimum and maximum values of the distribution. ****p < 0.0001