Table 3.
Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) for each ultrasound score, and hypothetical percentage of spared FNA depending on each score recommendations
| US score | Total FNA | Sensitivity | Specificity | PPV (CI 95%) | NPV (CI 95%) | Spared FNA (%) |
|---|---|---|---|---|---|---|
| KTIRADS | 6474 | 94.5% | 14.8% | 11.5% (± 0.8%; 10.7–12.3%) | 95.6% (± 1.3%; 94.3–96.9%) | 665 (10.3%) |
| ATA | 6016 | 84.5% | 19.5% | 7.7% (± 0.3%; 7.4–8%) | 94.1% (± 1.7%; 92.4–95.8%) | 682 (11.3%) |
| AACE/ACE-AME | 6474 | 50.1% | 50.3% | 8.4% (± 2.7%; 5.7–11.1%) | 91.7% (± 0.8%; 90.9–92.5%) | 2468 (38.1%) |
| EUTIRADS | 6474 | 80.6% | 20.7% | 10.8% (± 2%; 8.8–12.8%) | 89.9% (± 0.7%; 89.2–90.6%) | 1682 (25.9%) |
| ACRTIRADS | 6474 | 72.7% | 31.7% | 8.9% (± 1%; 7.9–9.9%) | 93.0% (± 1.3%; 91.7–94.3%) | 1324 (20.6%) |