Table 4.
Odds ratio of having various metabolic abnormalities in male career firefighters with borderline or low total testosterone (TT) levels compared to those with TT in the reference range.
| Total testosterone group | n | % | Crude analysis | Adjusted analysis# | ||
|---|---|---|---|---|---|---|
| OR (95%CI) | p | OR (95%CI) | p | |||
| Fatty liver + | ||||||
| Reference range TT (400–916 ng/dL) | 183 | 31.1 | 1.00 | – | 1.00 | – |
| Borderline TT (264–399 ng/dL) | 83 | 44.6 | 1.78* (1.04–3.03) | 0.04 | 1.29 (0.69–2.41) | 0.43 |
| Low TT (< 264 ng/dL) | 32 | 78.1 | 7.90* (3.23–19.31) | < 0.01 | 3.99* (1.45–10.94) | 0.01 |
| HbA1c ≥ 5.7% | ||||||
| Reference range TT (400–916 ng/dL) | 183 | 8.2 | 1.00 | – | 1.00 | – |
| Borderline TT (264–399 ng/dL) | 83 | 16.9 | 2.27* (1.04–4.96) | 0.04 | 1.79 (0.78–4.10) | 0.17 |
| Low TT (< 264 ng/dL) | 32 | 34.4 | 5.87* (2.38–14.44) | < 0.01 | 2.76* (1.01–7.53) | 0.05 |
| Triglycerides (≥ 150 mg/dL) | ||||||
| Reference range TT (400–916 ng/dL) | 183 | 18.6 | 1.00 | – | 1.00 | – |
| Borderline TT (264–399 ng/dL) | 83 | 33.7 | 2.23* (1.24–4.02) | 0.01 | 1.86* (1.00–3.46) | 0.05 |
| Low TT (< 264 ng/dL) | 32 | 68.8 | 9.64* (4.18–22.23) | < 0.01 | 6.36* (2.62–15.37) | < 0.01 |
| HDL-cholesterol < 40 mg/dL | ||||||
| Reference range TT (400–916 ng/dL) | 183 | 12.6 | 1.00 | – | 1.00 | – |
| Borderline TT (264–399 ng/dL) | 83 | 27.7 | 2.67* (1.39–5.10) | < 0.01 | 2.34* (1.20–4.57) | 0.1 |
| Low TT (< 264 ng/dL) | 32 | 37.5 | 4.17* (1.80–9.66) | < 0.01 | 2.42 (0.94–6.28) | 0.07 |
TT: total testosterone; p: Pearson’s Chi-square p-value.
#Adjusted for body mass index, age, and HbA1c; *Significantly different when compared to reference group.