Skip to main content
. 2021 Jul 9;12:4226. doi: 10.1038/s41467-021-24291-6

Fig. 1. Structure of RIFIN-V2 in complex with LAIR1.

Fig. 1

a Schematic view of A-RIFIN domains (upper, SP: Signal peptide; V1: Variable domain 1; P*: PEXEL motif; C1: Conserved domain 1; I*: Indel motif; V2: Variable domain 2; TM: Transmembrane domain; C2: Conserved domain 2). Structure of RIFIN (PF3D7_1040300) V2 domain in complex with antibody MGD21 LAIR1 domain is presented as cartoon side view (lower). RIFIN-V2 domain is colored in rainbow. LAIR1 domain is colored in cyan. All secondary structural elements are labeled. b, Surface and pockets on LAIR-1 that accommodate RIFIN-V2 apex. c Detail of RIFIN-LAIR1 interface. Interface residues are shown with side chains as sticks and labeled.