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. 2021 Jul 9;11:14186. doi: 10.1038/s41598-021-93616-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Identification of candidate gene targets of miR-378a. (a) Venn diagram shows the overlaps of genes down-regulated (DM) in cells transfected with miR-378a mimic for 24 h and 48 h and genes up-regulated (UI) in cells transfected with miR-378a inhibitor for 24 h and 48 h. (b) Venn diagram shows the overlaps of genes identified in (a) and target genes of miR-378a predicted by three different databases (see “Materials and methods” section).