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. 2021 Jul 9;11:14217. doi: 10.1038/s41598-021-93605-x

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Slice by slice comparison throughout the plaques of target-to-blood pool ratio versus fat fraction and intraplaque hemorrhage. The left panels in the columns show FF and TBR per MRI slice, the right panels R2* and TBR per MRI slice. TBR values are shown on the right y-axis in the figures. The slice numbers are shown on the x- axis, slice numbers differ, as plaque length varies between the patients. The comparison of the 12 patients shows a large heterogeneity in both FF and R2* dispersion and no significant correlation between FF and TBR and respectively R2* and TBR. All graphs were created using GraphPad Prism version 9.0.0 for Windows, GraphPad Software, San Diego, California USA, www.graphpad.com. FF fat fraction, TBR target-to-blood pool ratio.