Table 1.
T2 map—robust and reproducible features.
| Features | CCC | DR | Intra-observer ICC | Inter-observer ICC |
|---|---|---|---|---|
| shape_Maximum3DDiameter | 0.99205286 | 0.96251665 | 0.99716664 | 0.9867156 |
| shape_MajorAxisLength | 0.99793419 | 0.97981361 | 0.996171 | 0.99749429 |
| shape_Elongation | 0.9169208 | 0.92685464 | 0.99414914 | 0.99282215 |
| shape_Maximum2DDiameterSlice | 0.99383495 | 0.97822157 | 0.99761689 | 0.9936394 |
| shape_SurfaceArea | 0.99756368 | 0.93373906 | 0.99185998 | 0.87503941 |
| shape_MinorAxisLength | 0.99207422 | 0.96696735 | 0.99616827 | 0.99825783 |
| shape_Maximum2DDiameterColumn | 0.98837119 | 0.95757463 | 0.99194508 | 0.98736261 |
| shape_Maximum2DDiameterRow | 0.99209873 | 0.95395661 | 0.99386968 | 0.97679991 |
| gldm_GrayLevelVariance | 0.99604933 | 0.97096707 | 0.99580458 | 0.98995297 |
| gldm_HighGrayLevelEmphasis | 0.9987185 | 0.99001813 | 0.99867983 | 0.99895219 |
| gldm_DependenceEntropy | 0.9768604 | 0.93069293 | 0.97918853 | 0.95287381 |
| gldm_GrayLevelNonUniformity | 0.99672213 | 0.96844026 | 0.99404055 | 0.90588485 |
| gldm_SmallDependenceEmphasis | 0.99618473 | 0.97684637 | 0.99941963 | 0.99714743 |
| gldm_SmallDependenceHighGrayLevelEmphasis | 0.99785548 | 0.99026715 | 0.99849964 | 0.99848907 |
| gldm_DependenceNonUniformityNormalized | 0.98991352 | 0.97110551 | 0.99933187 | 0.99372596 |
| gldm_LargeDependenceEmphasis | 0.99604457 | 0.97768667 | 0.99663332 | 0.9956135 |
| gldm_DependenceVariance | 0.98074193 | 0.95832053 | 0.99468459 | 0.99131544 |
| gldm_LargeDependenceHighGrayLevelEmphasis | 0.91063923 | 0.95569232 | 0.99721749 | 0.9746251 |
| glcm_JointAverage | 0.99868486 | 0.98745931 | 0.99801085 | 0.99716702 |
| glcm_SumAverage | 0.99868486 | 0.98745931 | 0.99801085 | 0.99716702 |
| glcm_JointEntropy | 0.99586316 | 0.9719637 | 0.99865882 | 0.99477919 |
| glcm_ClusterShade | 0.9839736 | 0.96063188 | 0.99510842 | 0.99205699 |
| glcm_MaximumProbability | 0.97316718 | 0.95034713 | 0.98318707 | 0.97765663 |
| glcm_Idmn | 0.97708482 | 0.95808548 | 0.99843989 | 0.98992028 |
| glcm_JointEnergy | 0.99472158 | 0.97035282 | 0.98991929 | 0.9924416 |
| glcm_Contrast | 0.99878665 | 0.98414808 | 0.99899223 | 0.99747783 |
| glcm_DifferenceEntropy | 0.99888168 | 0.98304573 | 0.99946222 | 0.99795149 |
| glcm_InverseVariance | 0.99783829 | 0.98143622 | 0.99945029 | 0.99754584 |
| glcm_DifferenceVariance | 0.99659893 | 0.97714962 | 0.99846232 | 0.99813253 |
| glcm_Idn | 0.970345 | 0.9541169 | 0.99815628 | 0.98941716 |
| glcm_Idm | 0.99727834 | 0.98155574 | 0.99927382 | 0.99750192 |
| glcm_Correlation | 0.93000815 | 0.91942547 | 0.98138967 | 0.98861346 |
| glcm_Autocorrelation | 0.99882875 | 0.99071159 | 0.99869595 | 0.999001 |
| glcm_SumEntropy | 0.99415534 | 0.96610084 | 0.99671268 | 0.9937416 |
| glcm_MCC | 0.93302938 | 0.91561808 | 0.92970785 | 0.94261298 |
| glcm_SumSquares | 0.99716854 | 0.97213991 | 0.99724918 | 0.99249056 |
| glcm_ClusterProminence | 0.98931893 | 0.96491762 | 0.99077845 | 0.98964681 |
| glcm_Imc2 | 0.97815659 | 0.92212229 | 0.97592009 | 0.9396985 |
| glcm_Imc1 | 0.99777137 | 0.97086093 | 0.99426633 | 0.99035433 |
| glcm_DifferenceAverage | 0.99848775 | 0.98296153 | 0.99937115 | 0.99702514 |
| glcm_Id | 0.99726682 | 0.98139837 | 0.99930241 | 0.99748562 |
| glcm_ClusterTendency | 0.99642325 | 0.9699074 | 0.99671296 | 0.99142976 |
| firstorder_InterquartileRange | 0.99521994 | 0.97486054 | 0.99841554 | 0.99669589 |
| firstorder_Uniformity | 0.99336279 | 0.96426864 | 0.99280367 | 0.99113126 |
| firstorder_Median | 0.99824873 | 0.9849003 | 0.9999125 | 0.99978288 |
| firstorder_Energy | 0.99285535 | 0.95932458 | 0.99901088 | 0.92817079 |
| firstorder_RobustMeanAbsoluteDeviation | 0.99779342 | 0.97649493 | 0.99844399 | 0.99691045 |
| firstorder_MeanAbsoluteDeviation | 0.99844334 | 0.97694624 | 0.99821731 | 0.99604297 |
| firstorder_TotalEnergy | 0.99285535 | 0.95932458 | 0.99901088 | 0.92817079 |
| firstorder_RootMeanSquared | 0.99884074 | 0.98651296 | 0.99989506 | 0.9997983 |
| firstorder_90Percentile | 0.99935775 | 0.99013933 | 0.99995552 | 0.99994976 |
| firstorder_Minimum | 0.9698354 | 0.92185515 | 0.92678063 | 0.8563204 |
| firstorder_Entropy | 0.99424781 | 0.96641727 | 0.99700328 | 0.99412676 |
| firstorder_Variance | 0.99606424 | 0.97099704 | 0.99579973 | 0.98995292 |
| firstorder_10Percentile | 0.99778937 | 0.97865487 | 0.99899933 | 0.99627425 |
| firstorder_Kurtosis | 0.93847516 | 0.90984293 | 0.95408877 | 0.97436669 |
| firstorder_Mean | 0.99880578 | 0.98622651 | 0.99989669 | 0.99974019 |
| glrlm_GrayLevelVariance | 0.9958799 | 0.970434 | 0.99549048 | 0.98993049 |
| glrlm_GrayLevelNonUniformityNormalized | 0.99543004 | 0.96647932 | 0.99413525 | 0.99112422 |
| glrlm_RunVariance | 0.99473224 | 0.9734017 | 0.99380636 | 0.99548573 |
| glrlm_GrayLevelNonUniformity | 0.99949804 | 0.9674928 | 0.99614749 | 0.90009412 |
| glrlm_LongRunEmphasis | 0.99714509 | 0.97728321 | 0.99490007 | 0.99758722 |
| glrlm_ShortRunHighGrayLevelEmphasis | 0.99887822 | 0.9896169 | 0.99863031 | 0.99910028 |
| glrlm_ShortRunEmphasis | 0.99850478 | 0.9822178 | 0.99846149 | 0.99790335 |
| glrlm_LongRunHighGrayLevelEmphasis | 0.99248684 | 0.9784732 | 0.99830025 | 0.99622993 |
| glrlm_RunPercentage | 0.99663584 | 0.97947032 | 0.99853888 | 0.99734065 |
| glrlm_RunEntropy | 0.99144107 | 0.95450254 | 0.99513693 | 0.98727089 |
| glrlm_HighGrayLevelRunEmphasis | 0.99875561 | 0.98967427 | 0.99862958 | 0.99894877 |
| glrlm_RunLengthNonUniformityNormalized | 0.99765911 | 0.98130563 | 0.99893779 | 0.99778324 |
| glszm_GrayLevelVariance | 0.9664123 | 0.93487499 | 0.97426499 | 0.97948862 |
| glszm_ZoneVariance | 0.99376813 | 0.97889386 | 0.98567831 | 0.91246949 |
| glszm_GrayLevelNonUniformityNormalized | 0.97487458 | 0.93998164 | 0.99321227 | 0.98660887 |
| glszm_SizeZoneNonUniformityNormalized | 0.96600087 | 0.93446205 | 0.99453147 | 0.97741752 |
| glszm_SizeZoneNonUniformity | 0.97920816 | 0.92353173 | 0.99747104 | 0.77391648 |
| glszm_LargeAreaEmphasis | 0.99376008 | 0.97890241 | 0.98569335 | 0.91286785 |
| glszm_SmallAreaHighGrayLevelEmphasis | 0.99850607 | 0.98619218 | 0.9981323 | 0.99889261 |
| glszm_ZonePercentage | 0.99601524 | 0.97623238 | 0.99938994 | 0.99740069 |
| glszm_LargeAreaLowGrayLevelEmphasis | 0.95717008 | 0.96966115 | 0.94344936 | 0.94615198 |
| glszm_HighGrayLevelZoneEmphasis | 0.99826972 | 0.98491803 | 0.99815622 | 0.99876604 |
| glszm_SmallAreaEmphasis | 0.96165228 | 0.93147704 | 0.99401327 | 0.9749973 |
| glszm_ZoneEntropy | 0.95503524 | 0.92776222 | 0.96164933 | 0.96298698 |
| ngtdm_Complexity | 0.97512148 | 0.95607862 | 0.97876807 | 0.98862786 |
| ngtdm_Contrast | 0.99332362 | 0.9725499 | 0.99853608 | 0.99306747 |
| ngtdm_Busyness | 0.99582432 | 0.93702781 | 0.96571588 | 0.9623215 |
T2 map acquisition robust and reproducible features as defined by CCC & DR ≥ 0.9 and inter-/intra-ICC ≥ 0.75. CCC, concordance correlation coefficient; DR, dynamic range; firstorder, first-order features; GLCM, gray level co-occurrence matrix; GLDM, gray level difference matrix; GLRLM, gray level run length matrix; GLSZM, gray level size zone matrix; ICC, intraclass correlation coefficient; NGTDM, neighboring gray tone difference matrix. https://pyradiomics.readthedocs.io19.