Table 1.

Techniques used for non-nanofibrous scaffold fabrication

Method	Advantages	Disadvantages	Ref
Gas foaming	Free from organic solvents Operates at less temperature	Inadequate pore interconnectivity Low mechanical strength	Khang (2017)
Rapid prototyping	Ease of attaining desired fiber architecture Controlled geometry, porosity and pore size Custom-made and accurate pore structure No need of supporting material	High temperature requirement Expensive equipment	Khang (2017)
Injectable gel	Ease of incorporating functional bioactive compounds Intricate scaffolds can be fabricated	–	Khang (2017)
Solvent casting	Simple, easy and cost effective scaffold fabrication Does not demand sophisticated equipment	Toxic solvents usage More time is required for solvent evaporation Scaffolds might be toxic due to presence of solvent traces	Subia et al. (2010)
Particulate-leaching technique	Process is easy to carry out Scaffolds with precise pore size can be achieved Requires lesser polymer content to fabricate Pore size (~ 500 μm) and 94–95% of porosity	It is difficult to control inter-pore spacing’s and pore shape	Subia et al. (2010)
Fiber mesh	Higher surface area	Scaffolds possess less dimensional stability	Subia et al. (2010)