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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Dev Psychobiol. 2021 Jan 10;63(5):890–902. doi: 10.1002/dev.22085

Table 3.

Direct and indirect effects (through age at menarche) of trauma, abuse, and neglect on

Horvath acceleration, accounting for cell counts (CD8naive, CD8pCD28nCD45Ran).

Predictor Outcome b SE ß p 95% CI
Trauma Age Acceleration 0.01 0.05 .03 .80 [−0.08, 0.11]
Menarche Age Acceleration −0.38 0.20 −.15 .06 [−0.78, 0.01]
CD8naive Age Acceleration −0.01 0.01 −.06 .52 [−0.02, 0.01]
CD8pCD28nCD45Ran Age Acceleration −0.05 0.09 −.04 .63 [−0.23, 0.14]
Trauma Menarche −0.02 0.02 −.09 .42 [−0.05, 0.02]
CD8naive Menarche −0.01 <.01 −.16 .19 [−0.01, <.01]
CD8pCD28nCD45Ran Menarche −0.05 0.05 −.12 .28 [−0.15, 0.04]
Indirect Effect through Menarche 0.01 0.01 .01 .48 [−0.01, 0.02]

Abuse Age Acceleration 0.02 0.06 .03 .81 [−0.11, 0.14]
Menarche Age Acceleration −0.37 0.20 −.15 .06 [−0.77, 0.02]
CD8naive Age Acceleration <0.01 0.01 −.05 .64 [−0.02, 0.01]
CD8pCD28nCD45Ran Age Acceleration −0.03 0.09 −.03 .74 [−0.22, 0.15]
Abuse Age Acceleration −0.03 0.02 −.11 .28 [−0.07, 0.02]
CD8naive Menarche −0.01 <.01 −.15 .21 [−0.01, <.01]
CD8pCD28nCD45Ran Menarche −0.05 0.05 −.12 .30 [−0.14, 0.04]
Indirect Effect through Menarche 0.01 0.01 0.02 .38 [−0.01, 0.03]

Neglect Age Acceleration <0.01 0.15 <.01 .98 [−0.29, 0.29]
Menarche Age Acceleration −0.38 0.20 −.15 .06 [−0.77, 0.02]
CD8naive Age Acceleration −0.01 0.01 −.09 .33 [−0.02, 0.01]
CD8pCD28nCD45Ran Age Acceleration −0.05 0.09 −.05 .58 [−0.24, 0.13]
Neglect Menarche 0.03 0.06 .04 .66 [−0.10, 0.15]
CD8naive Menarche −0.01 <.01 −.19 .09 [−0.01, <.01]
CD8pCD28nCD45Ran Menarche −0.06 0.05 −.13 .21 [−0.15, 0.03]
Indirect Effect through Menarche −0.01 0.02 0.01 .65 [−0.06, 0.04]