Table 2.
Reported Outcome After DAIR, Stratified for Micro-Organism and/or Type of Joint Using Individual Patient Data From 64 Included Studies
| Micro-Organism and/or Type of Joint | n Studiesa |
n Patientsa | Pooled Success Rate of All Individual Patient Data |
RR (95% CI)b |
|---|---|---|---|---|
| All | 64 | 4380 | 60% | - |
| Per micro-organism | ||||
| Staphylococcus aureus | 54 | 2922 | 61% | ref. |
| CNS | 36 | 761 | 74% | 1.50 (1.32–1.70) |
| Per Affected Joint | ||||
| Knee | 27 | 1106 | 55% | ref. |
| Hip | 24 | 904 | 69% | 1.45 (1.29–1.63) |
| Per Affected Joint and Micro-Organism | ||||
| S aureus knee PJI | 19 | 692 | 54% | ref. |
| CNS knee PJI | 12 | 187 | 73% | 1.72 (1.33–2.21) |
| S aureus hip PJI | 19 | 547 | 69% | 1.48 (1.27–1.72) |
| CNS hip PJI | 13 | 145 | 83% | 2.66 (1.85–3.84) |
Abbreviations: CI, confidence interval; CNS, coagulase-negative staphylococci; DAIR, debridement, antibiotics, and retention of the implant; PJI, prosthetic joint infection; ref., reference category; RR, risk ratio.
aThe columns ‘n studies’ and ‘n patients’ displays the number of studies and patients for which the specific outcome regarding affected joint and/or micro-organism was reported. For example: one study could report outcome for both S aureus and CNS but not stratifying outcome for type of joint, whereas other studies only reported outcome for the total population without stratification for either type of joint or micro-organism. Therefore, numbers in this table cannot be summed.
bRelative risks for success were calculated for micro-organisms (with S aureus PJI as reference), for type of joint (with knee PJI as a reference), and for the 4 groups (with S aureus knee PJI as a reference).