Table 2.
Short-term follow-up; Patients who did not develop breast cancer ipsilateral to the biopsy site (n = 815) compared to patients who did develop breast cancer ipsilateral to the biopsy site (n = 8).
| No breast cancer subsequent to biopsy (n = 815) | Breast cancer subsequent to biopsy (n = 8) | p-value | |
|---|---|---|---|
| Mean age ± sd, in years, at moment of first biopsy | 55.7 ± 10.3 | 59.4 ± 10.2 | 0.243 |
| Referrer | 0.004 | ||
| National screening program | 416 (51.0%) | ||
| General practitioner | 186 (22.8%) | 2 (25.0%) | |
| Follow up | 209 (25.6%) | 6 (75.0%) | |
| Biopsy for other hospital | 4 (0.5%) | ||
| In case of referral by follow-up, specification reason for follow-up | 0.129 | ||
| History of breast cancer | 90 (11.0%) | 6 (75.0%) | |
| History/analysis of other malignancy than breast cancer | 7 (0.9%) | ||
| Family history of breast cancer | 42 (5.1%) | ||
| Detected benign lesion | 65 (8.0%) | ||
| Hormonal drug therapy | 4 (0.5%) | ||
| Preoperative screening | 1 (0.1%) | ||
| History of breast cancer | <0.001 | ||
| No | 717 (88.0%) | 2 (25.0%) | |
| Yes | 91 (11.2%) | 6 (75.0%) | |
| Missing | 7 (0.9%) | ||
| In case of history of breast cancer, side cancer compared to calcifications | 1.000 | ||
| Ipsilateral | 39 (4.9%) | 2 (25.0%) | |
| Contralateral | 52 (6.4%) | 4 (50.0%) | |
| Median time to diagnosis, in years | 2.4 (1.1–2.7) | ||
| Spatial relationship between future development of ipsilateral breast cancer and previous biopsy site | |||
| Biopsy site (biopsied quadrant) | 5 (62.5%) | ||
| Other quadrant | 3 (37.5%) | ||