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. 2021 Jun 25;24(7):102773. doi: 10.1016/j.isci.2021.102773

Figure 1.

Figure 1

Spaceflight affects ATF7-binding profile in TGCs

(A) Heatmap of signal intensities from ATF7 ChIP-seq data using GC/MG TGCs across ATF7-target genes in GC TGCs. Raw reads were scaled to mapped regions in each sample (reads per million).

(B) Typical ATF7-binding sites for cluster_1 (top), cluster_2 (bottom, left), and cluster_3 (bottom, right). Blue signals indicate the number of raw reads, normalized against total reads in each sample and region. Light orange boxes indicate ATF7-binding sites.

(C) Pathway analysis of cluster_1 genes using Reactome datasets. The top five pathways are shown, ranked by p value (Bonferroni correction for multiple testing).