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. 2020 Jul 12;50(3):916–928. doi: 10.1093/ije/dyaa098

Table 2.

Intention-to-treat effects of access to managed aquifer recharge water on blood pressure and urine total protein

Outcomes Model 1
Model 2
Model 3
Regression coefficienta (95% CI) p-value Regression coefficienta (95% CI) p-value Regression coefficienta (95% CI) p-value
All participants (N = 2911 person-visits for managed aquifer recharge water access and N = 2834 for no access)
Systolic BP in mmHg (mean difference) 1.96 (0.65, 3.28) 0.003 1.94 (0.63, 3.25) 0.004 1.96 (0.66, 3.26) 0.003
Diastolic BP in mmHg (mean difference) 1.46 (0.41, 2.51) 0.006 1.43 (0.38, 2.49) 0.008 1.44 (0.40, 2.48) 0.007
Mean arterial pressure in mmHg (mean difference) 1.63 (0.52, 2.74) 0.004 1.60 (0.49, 2.71) 0.005 1.62 (0.52, 2.71) 0.004
Pulse pressure in mmHg (mean difference) 0.50 (−0.07, 1.07) 0.087 0.50 (−0.04, 1.05) 0.070 0.53 (−0.02, 1.07) 0.057
Urinary total proteinb (ratio of medians) 1.10 (0.91, 1.33) 0.337 1.10 (0.91, 1.33) 0.326 1.11 (0.92, 1.35) 0.277
Analyses restricted among non-hypertensive, non-diabetic, non-pregnant and no-kidney-disease participants (N = 2301 person-visits for managed aquifer recharge water access and N = 2220 for no access)
Systolic BP in mmHg (mean difference) 1.38 (0.01, 2.75) 0.049 1.40 (0.00, 2.80) 0.050 1.41 (0.01, 2.80) 0.048
Diastolic BP in mmHg (mean difference) 1.34 (0.22, 2.46) 0.019 1.33 (0.21, 2.45) 0.020 1.32 (0.21, 2.44) 0.020
Mean arterial pressure in mmHg (mean difference) 1.35 (0.18, 2.53) 0.024 1.35 (0.17, 2.54) 0.026 1.35 (0.17, 2.53) 0.025
Pulse pressure in mmHg (mean difference) 0.05 (−0.52, 0.61) 0.871 0.08 (−0.50, 0.65) 0.796 0.10 (−0.46, 0.67) 0.723
Urinary total proteinb (ratio of medians) 1.10 (0.91, 1.34) 0.337 1.11 (0.91, 1.35) 0.305 1.11 (0.92, 1.35) 0.276
a

Refers to difference in mean blood pressure of participants or ratio of medians of 24-hour urinary protein of person-visits between communities with access to managed aquifer recharge water and without access.

b

Analyses restricted to complete 24-hour urine samples only.

N = 1085 for person-visits from the access to managed aquifer recharge water group. N = 1060 for person-visits from the no access to managed aquifer recharge water group (reference).

Model 1: adjusted for visit only; Model 2: adjusted for visit, age, sex and body mass index; Model 3: adjusted for age, sex, body mass index, marital status, physical activity, smoking status, alcohol consumption, hours of sleep, religion, salt intake and wealth quintile.