Table 2.
Results of Simple Logistic Regression Analysis of Association of Variables With Drug Shortage Risk
| Variable | Odds Ratio (95% CI) |
|---|---|
| Dosage form | |
| Other | [Reference] |
| Oral only | 0.14 (0.078-0.25) |
| Oral and IV | 1.67 (1.06-2.66) |
| IV only | 2.85 (1.87-4.40) |
| Therapeutic class | |
| Other | [Reference] |
| Antipsychotica | 0.96 (0.28-2.57) |
| Antineoplastica | 1.13 (0.63-1.95) |
| Cardiovascular | 3.07 (2.01-4.67) |
| Antimicrobial | 3.84 (2.50-5.90) |
| Analgesic | 5.57 (3.35-9.30) |
| Anesthetic | 16.54 (5.49-61.00) |
| Electrolyte | 150.36 (45.26-932.70) |
| Controlled substance schedule | |
| Schedules III–Va | 1.28 (0.65-2.77) |
| Schedule IIa | 1.36 (0.78-2.32) |
| Orphan drug status | 0.29 (0.17-0.46) |
| Branded/generic product availability | |
| Other | [Reference] |
| Branded only | 0.24 (0.15-0.38) |
| Generic only | 2.11 (1.57-2.85) |
| No. of manufacturers | 0.33 (0.25-0.44) |
Abbreviations: CI, confidence interval; IV, intravenous.
a P > 0.05 for comparison with reference.