TABLE 3.
Gene Ontology Enrichment Analysis for DEPs in male plasma protein across the life course (FDR 5%)
| Males | ||||
|---|---|---|---|---|
| Enrichment FDR | Genes in list | Total genes | Functional Category | |
| Juvenile‐Adult | 8.26E‐07 | 7 | 83 | ECM‐receptor interaction |
| 2.69E‐04 | 5 | 88 | Complement and coagulation cascades | |
| 9.46E‐04 | 6 | 198 | Focal adhesion | |
| 2.28E‐03 | 4 | 90 | Protein digestion and absorption | |
| 3.41E‐03 | 3 | 47 | Malaria | |
| 4.88E‐03 | 4 | 123 | Platelet activation | |
| 7.19E‐03 | 6 | 353 | PI3K‐Akt signaling pathway | |
| 7.19E‐03 | 6 | 348 | Human papillomavirus infection | |
| 1.44E‐02 | 3 | 101 | AGE‐RAGE signaling pathway in diabetic complications | |
| 1.44E‐02 | 2 | 34 | Prion diseases | |
| Juvenile‐Aged | 5.72E‐13 | 16 | 88 | Complement and coagulation cascades |
| 5.27E‐05 | 11 | 142 | Fluid shear stress and atherosclerosis | |
| 4.06E‐04 | 8 | 90 | Protein digestion and absorption | |
| 9.51E‐04 | 7 | 77 | Biosynthesis of amino acids | |
| 1.24E‐03 | 7 | 83 | ECM‐receptor interaction | |
| 1.94E‐03 | 6 | 64 | Glutathione metabolism | |
| 1.94E‐03 | 10 | 198 | Focal adhesion | |
| 3.86E‐03 | 6 | 76 | Pertussis | |
| 7.95E‐03 | 7 | 123 | Platelet activation | |
| 9.40E‐03 | 4 | 36 | African trypanosomiasis | |
| Adult‐Aged | No Clustering | |||