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. 2021 Jul 3;13(13):2208. doi: 10.3390/polym13132208

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of the MAN-CS-OVA-PLGA-MPs on OVA-specific IgG and IgG subtypes in serum of mice. (A) Serum samples were collected for ELISA from immunized ICR mice in all groups between 14–42 days following the first immunization. (B) The OVA-specific IgG (A) and IgG isotype (IgG2a, IgG2b, and IgG1) serum levels were determined by ELISA as described in Section 2. The concentrations of IgG and IgG isotopes are presented as mean ± standard deviation. * p < 0.05, ** p < 0.01 compared with OVA; # p < 0.05 compared with CS-OVA-PLGA-MPs. Results are presented as the mean ± SD (n = 3).