Figure 4.
Ligand binding into the active site of COX-2. Protein backbone is represented in the background as a ribbon and only key residues are highlighted. (A) Superimposed binding modes of the MEF (green), MNA (purple), NB (yellow), MC (cyan), NAP (orange), and DIC (brown). The ligands are also shown separately: (B) MEF, (C) MNA, (D) NB, (E) MC, (F) NAP, and (G) DIC.