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. 2021 Jul 2;26(13):4061. doi: 10.3390/molecules26134061

Table 6.

Antifungal activity of tested compounds (MIC and MBC in mg/mL).

Compounds A.f. A.n. A.v. P.f. T.v. P.v.c.
1 MIC >1.00 0.50 ± 0.00 0.50 ± 0.00 0.50 ± 0.02 0.50 ± 0.00 0.50 ± 0.02
MFC >1.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
2 MIC >1.00 0.50 ± 0.00 1.00 ± 0.00 0.50 ± 0.00 0.50 ± 0.00 1.00 ± 0.00
MFC >1.00 1.00 ± 0.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 >1.00
3 MIC >1.00 1.00 ± 0.00 1.00 ± 0.00 0.50 ± 0.00 0.50 ± 0.02 0.50 ± 0.00
MFC >1.00 >1.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
4 MIC 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.02 0.50 ± 0.02 1.00 ± 0.00 >1.00
MFC >1.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 >1.00 >1.00
5 MIC >1.00 >1.00 >1.00 >1.00 >1.00 >1.00
MFC >1.00 >1.00 >1.00 >1.00 >1.00 >1.00
6 MIC >1.00 >1.00 0.25 ± 0.00 0.25 ± 0.04 0.25 ± 0.04 0.25 ± 0.04
MFC >1.00 >1.00 0.50 ± 0.02 0.50 ± 0.02 0.50 ± 0.02 0.50 ± 0.02
7 MIC 0.50 ± 0.00 1.00 ± 0.00 0.25 ± 0.04 0.50 ± 0.00 0.50 ± 0.00 0.50 ± 0.00
MFC 1.00 ± 0.00 >1.00 0.50 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
8 MIC >1.00 >1.00 0.50 ± 0.00 0.50 ± 0.00 0.50 ± 0.00 0.50 ± 0.00
MFC >1.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
9 MIC 0.50 ± 0.02 1.00 ± 0.00 0.25 ± 0.00 0.50 ± 0.00 0.25 ± 0.00 0.50 ± 0.00
MFC 1.00 ± 0.00 >1.00 0.50 ± 0.00 1.00 ± 0.00 0.50 ± 0.00 0.83 ± 0.11
10 MIC 0.50 ± 0.02 1.00 ± 0.00 0.25 ± 0.00 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.02
MBC 1.00 ± 0.00 >1.00 0.50 ± 0.03 >1.00 1.00 ± 0.00 1.00 ± 0.00
11 MIC 1.00 ± 0.00 >1.00 0.50 ± 0.01 0.50 ± 0.03 0.25 ± 0.00 0.50 ± 0.00
MBC >1.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 0.50 ± 0.02 1.00 ± 0.00
12 MIC 0.50 ± 0.02 1.00 ± 0.00 0.50 ± 0.02 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.02
MBC 1.00 ± 0.00 >1.00 1.00 ± 0.00 >1.00 1.00 ± 0.00 1.00 ± 0.00
13 MIC 1.00 ± 0.00 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.02 0.50 ± 0.03 0.50 ± 0.03
MBC >1.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
14 MIC 1.00 ± 0.00 0.50 ± 0.03 0.25 ± 0.00 0.50 ± 0.03 0.50 ± 0.03 0.50 ± 0.02
MBC >1.00 1.00 ± 0.00 0.50 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00
15 MIC 1.00 ± 0.00 >1.00 1.00 ± 0.00 0.50 ± 0.00 0.50 ± 0.02 0.25 ± 0.00
MBC >1.00 >1.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 0.50 ± 0.02
16 MIC 0.12 ± 0.00 1.00 ± 0.00 0.50 ± 0.00 0.50 ± 0.02 0.50 ± 0.02 1.00 ± 0.00
MBC 0.25 ± 0.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 1.00 ± 0.00 >1.00
17 MIC 1.00 ± 0.00 >1.00 0.50 ± 0.02 0.50 ± 0.02 0.25 ± 0.00 0.25 ± 0.00
MBC >1.00 >1.00 1.00 ± 0.00 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.00
18 MIC 0.50 ± 0.01 0.50 ± 0.02 0.12 ± 0.00 0.50 ± 0.02 0.25 ± 0.00 0.25 ± 0.04
MBC 1.00 ± 0.00 1.00 ± 0.00 0.25 ± 0.00 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.02
19 MIC 0.50 ± 0.03 0.50 ± 0.00 0.25 ± 0.04 0.25 ± 0.00 0.25 ± 0.00 0.12 ± 0.00
MBC 1.00 ± 0.00 1.00 ± 0.00 0.50 ± 0.02 0.50 ± 0.02 0.50 ± 0.02 0.25 ± 0.01
Bifonazole MIC 1.00 ± 0.00 >1.00 1.00 ± 0.00 0.50 ± 0.00 0.50 ± 0.02 0.25 ± 0.00
MFC 0.20 ± 0.000 0.20 ± 0.000 0.20 ± 0.01 0.25 ± 0.01 0.20 ± 0.01 0.20 ± 0.00
Ketoconazole MIC 0.20 ± 0.01 0.20 ± 0.01 0.20 ± 0.00 0.20 ± 0.00 1.00 ± 0.01 0.20 ± 0.01
MFC 0.50 ± 0.03 0.50 ± 0.03 0.50 ± 0.02 0.50 ± 0.03 1.50 ± 0.02 0.30 ± 0.01

A.v.—A. versicolor (ATCC 11730), T.v.—T. viride (IAM 5061), A.n.—A. niger (ATCC 6275), P.v.c.—Penicillium verrucosum var. cyclopium (food isolate). P.f.—P. funiculosum (ATCC 36839), A.f.—A. fumigatus (human isolate).