Table 1.

Extraction methods, solvent, advantages, and disadvantages.

Method	Solvent	Advantages	Disadvantages	References
QuEChERS	Acetonitrile, acetonitrile/acetic acid, acetonitrile/citric acid, acetonitrile/formic acid	Fast, simple, economical, reproducibility and applicability	Low enrichment factor in extracts of lipophilic compounds and the need for original modifications of the procedure	[53,54,55]
LLE	Hexane, cyclohexane	Effective for small-scale preparations	Does not provide a sufficiently clean analyte in all cases, time-consuming, possible loss of sample by adsorption onto the glassware	[45,49,56]
SLE	Acetonitrile/water, methanol/water	Smaller volumes of solvent	SLE alone can be not satisfactory to extract some mycotoxins without interference and additional purification steps are usually needed	[47,49]
PLE	Acetonitrile/water, acetonitrile/methanol	Extraction process can be automated, higher extraction efficiency in shorter time, lower amount of extraction solvent	High instrument price	[47,49,57]
SFE	supercritical CO2 fluid, acetonitrile	Fast, small solvent volumes, extraction of temperature sensible analytes	Low recoveries, high concentrations of co-extracts, high costs	[45,49]