Table 2.

Comparison of conventional and microfluidic production methods of microparticles and liposomes

Fabrication method	Advantages	Disadvantages	Ref.
Conventional	Mass production Simple and rapid	Broad size distributions Poor batch‐to‐batch reproducibility Post processing is required Larger volumes‐costly Difficult to control	[ 65 , 66 , 67 ]
Microfluidics	Reproducibility High throughput Narrow size distribution Control over size distribution Large scale manufacturing Precision processing Small volumes Flexibility in experimental design	Fabrication and microfluidic skills needed Low control over particle shape Low final concentrations in end product	[ 71 , 72 , 73 , 74 ]