Table 6.

Lignans and their derivatives isolated from Zanthoxylum species with anti-inflammatory, antispasmodic, anti-thrombotic, antioxidant, cardioprotective and antiulcer activities.

Isolated Compound	Biological Activities	Part of Plant	Refs.
Zanthpodocarpins A and B,	Anti-Inflammatory activity	Z. bungeanum barks	[63,65]
Eudesmin	Anti-inflammatory activity	Z. bungeanum barks	[63,65]
(1R,2R,5R,6S)-2-(3,4-Dimethoxyphenyl)-6-(3,4-dihydroxyphenyl)-3,7-ioxabicyclo[3.3.0]octane	Anti-inflammatory activity	Z. bungeanum barks	[63,65]
Magnone A	Anti-inflammatory activity	Z. bungeanum barks	[63,65]
rel-(1R,5R,6S)-6-(4-hydroxy-3-Methoxyphenyl)-3,7-dioxabicyclo[3.3.0]octan-2-one	Anti-inflammatory activity	Z. bungeanum barks	[63,65]
Dimethoxysamin	Anti-inflammatory activity	Z. bungeanum barks	[63,65]
Zanthpodocarpins C-H	Anti-inflammatory activity	Z. bungeanum barks	[63,65]
Fargesin	Anti-inflammatory activity	Z. armatum root and stem	[124]
Kobusin	Anti-inflammatory activity	Z. armatum root and stem	[124]
Planispine A	Anti-inflammatory activity	Z. armatum root and stem	[124]
Pinoresinol-di-3,3-dimethylallyl	Anti-inflammatory activity	Z. armatum root and stem	[124]
Pinoresinol	Antispasmodic activity	Z. nitidum leaves	[120]
Medioresinol	Antispasmodic activity	Z. nitidum leaves	[120]
Piperitol-3,3-dimethylallyl ether	Anti-thrombotic activity	Z. nitidum stem bark	[110]
(+)-Sesamin	Antioxidant and chemopreventive activities	Z. zanthoxyloides fruits	[58]
Hydroxy-α-sanshool	Cardioprotective activity	Z. bungeanum fruits	[125]
hydroxy-β-sanshool	Cardioprotective activity	Z. bungeanum fruits	[125]
L-sesamin	Antiulcer activity	Z. nitidum root	[56]