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. 2021 Jul 3;26(13):4078. doi: 10.3390/molecules26134078

Table 3.

The solubility values of phenacetin expressed as molar fractions (×103) along with the standard uncertainty (n = 3) determined in six neat solvents.

T [K] 298.15 303.15 308.15 313.15
water (10) 0.89 ± 0.05 1.11 ± 0.05 1.50 ± 0.05 2.07 ± 0.09
acetonitrile 11.81 ± 0.73 13.69 ± 0.28 16.10 ± 0.80 19.01 ± 0.45
1,4-dioxane 9.1 ± 0.5 12.4 ± 0.5 16.2 ± 0.6 20.3 ± 0.6
DMF 73.7 ± 1.6 86.9 ± 3.1 104.7 ± 3.3 124.6 ± 3.5
DMSO 34.1 ± 3.2 52.7 ± 2.7 77.2 ± 2.9 108.1 ± 5.0
methanol 19.6 ± 1.4 24.6 ± 1.2 31.6 ± 1.2 41.2 ± 1.1