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. 2021 Jul 10;21:798. doi: 10.1186/s12885-021-08538-5

Table 2.

The fibrosis indexes of the study subjects in the PSM cohorts

Variables Tamoxifen (n = 154) Toremifene (n = 154) P-value
APRI at baseline 0.23 [0.19–0.30] 0.22 [0.18–0.27] 0.052
APRI at follow-up time 0.30 [0.26–0.37] 0.25 [0.22–0.34] < 0.001
P-value < 0.001 < 0.001
Medium or high APRI at baseline 4 (2.6) 3 (1.9) 1.000
Medium or high APRI at follow-up time 15 (9.7) 4 (2.6) 0.009
P-value 0.009 1.000
FIB-4 at baseline 0.99 [0.79–1.20] 0.93 [0.77–1.11] 0.095
FIB-4 at follow-up time 1.13 [0.92,1.35] 1.04 [0.87,1.30] 0.034
P-value < 0.001 < 0.001
Medium or high FIB-4 at baseline 28 (18.2) 18 (11.7) 0.110
Medium or high FIB-4 at follow-up time 45 (29.2) 37 (24.0) 0.302
P-value 0.023 0.004

Statistically significant values are highlighted in italics

Data are presented as the mean ± standard deviation, median [interquartile range] or number (%)

Abbreviations: APRI aspartate aminotransferase-platelet ratio index; FIB-4 Fibrosis- 4 index