Table 3.
Comparison of specific DNA methylation sites between women with term and preterm births after pyrosequencing
| Variable | Target ID† of differentially methylated site | Term (n = 39) | Preterm (n = 43) | p-value |
|---|---|---|---|---|
| VTRNA2-1_pos1 | cg04481923 | 25.8 ± 20.9 | 33.9 ± 18.6 | 0.065 |
| VTRNA2-1_pos2 | 26.3 ± 22.2 | 35.2 ± 19.5 | 0.045a | |
| VTRNA2-1_pos3 | 27.4 ± 22.3 | 36.4 ± 19.8 | 0.026a |
Data are presented as the mean ± SD
VTRNA2-1_pos1, _pos2, and _pos3 were analyzed by pyrosequencing as CpG sites of chromosome 5:135,416,205, chromosome 5:135,416,207, and chromosome 5:135,416,214, respectively
VTRNA2-1 vault RNA 2 − 1
aMann–Whitney U-test, p < 0.05
†Name of the probe