Table 1.
Methylation-driven genes in TCGA-UCEC
| Gene | normalMean | TumorMean | logFC | pValue | cor | corPavlue | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZIC1 | 0.24388423 | 0.480909 | 0.97956742 | 3.86E−27 | − 0.358903 | 1.31E−14 | ||||||
| DDR2 | 0.53360917 | 0.78946164 | 0.5650857 | 5.41E−27 | − 0.3282384 | 2.46E−12 | ||||||
| ZNF454 | 0.16962317 | 0.49986881 | 1.55921625 | 5.91E−27 | − 0.4837467 | 8.84E−27 | ||||||
| PARVG | 0.44800915 | 0.2361113 | − 0.9240611 | 2.47E−26 | − 0.3172147 | 1.41E−11 | ||||||
| SEPHS2 | 0.28267773 | 0.16730021 | − 0.756719 | 3.28E−26 | − 0.4605881 | 4.00E−24 | ||||||
| GYPC | 0.28342815 | 0.5133146 | 0.85686022 | 8.16E−26 | − 0.3504962 | 5.83E−14 | ||||||
| HIST1H3E | 0.25147232 | 0.48165462 | 0.9375994 | 9.75E−26 | − 0.3425503 | 2.30E−13 | ||||||
| HAND2 | 0.20123389 | 0.46384627 | 1.20477346 | 1.36E−25 | − 0.3498187 | 6.56E−14 | ||||||
| CDO1 | 0.29599759 | 0.56098126 | 0.92236715 | 1.82E−25 | − 0.455063 | 1.61E−23 | ||||||
| ELF3 | 0.50067406 | 0.32635135 | − 0.6174457 | 2.48E−25 | − 0.3996758 | 4.88E−18 | ||||||
| CCDC181 | 0.28894174 | 0.55897974 | 0.95201739 | 3.26E−25 | − 0.3601706 | 1.04E−14 | ||||||
| ZNF582 | 0.11179343 | 0.29681801 | 1.4087432 | 8.65E−25 | − 0.5675056 | 2.82E−38 | ||||||
| CLDN4 | 0.4338084 | 0.28653612 | − 0.598341 | 1.64E−24 | − 0.3226787 | 5.99E−12 | ||||||
| MUC1 | 0.39993189 | 0.21303751 | − 0.9086469 | 4.80E−24 | − 0.4433414 | 2.83E−22 | ||||||
| RNF43 | 0.29871314 | 0.14721458 | − 1.0208401 | 5.08E−24 | − 0.3486804 | 8.00E−14 | ||||||
| SOX11 | 0.14442811 | 0.4895337 | 1.76105668 | 8.68E−24 | − 0.4199562 | 6.28E−20 | ||||||
| ZNF334 | 0.17865714 | 0.41878261 | 1.229008 | 9.40E−24 | − 0.4800659 | 2.41E−26 | ||||||
| VSIG2 | 0.50192277 | 0.74041012 | 0.56085922 | 1.33E−23 | − 0.5896991 | 6.59E−42 | ||||||
| SYNE4 | 0.30599367 | 0.18129516 | − 0.7551614 | 4.99E−23 | − 0.4613683 | 3.28E−24 | ||||||
| MAP10 | 0.31229235 | 0.52780824 | 0.75711664 | 1.47E−22 | − 0.5832404 | 8.02E−41 | ||||||
| AKNA | 0.25605955 | 0.36468253 | 0.51016171 | 4.19E−22 | − 0.3612481 | 8.57E−15 | ||||||
| RAB25 | 0.33919528 | 0.20764432 | − 0.7080017 | 1.53E−21 | − 0.5555928 | 1.94E−36 | ||||||
| VAMP5 | 0.32375158 | 0.47780114 | 0.56152305 | 2.60E−21 | − 0.3432457 | 2.04E−13 | ||||||
| ZNF677 | 0.2289589 | 0.37276287 | 0.70316948 | 3.67E−20 | − 0.5031252 | 3.66E−29 | ||||||
| MFAP4 | 0.34031638 | 0.52691515 | 0.63069407 | 6.07E−20 | − 0.3764796 | 4.99E−16 | ||||||
| HAAO | 0.22510224 | 0.42993225 | 0.93352892 | 2.24E−19 | − 0.3908538 | 2.96E−17 | ||||||
| EFS | 0.19074443 | 0.45628049 | 1.25828004 | 1.24E−18 | − 0.5860014 | 2.78E−41 | ||||||
| ZNF502 | 0.32342026 | 0.55929393 | 0.79019662 | 4.87E−18 | − 0.7615427 | 3.34E−83 | ||||||
| ST6GALNAC1 | 0.52377837 | 0.35028925 | − 0.5804098 | 1.23E−17 | − 0.3588641 | 1.32E−14 | ||||||
| SNCA | 0.14417966 | 0.29249887 | 1.02056345 | 2.99E−17 | − 0.3170668 | 1.44E−11 | ||||||
| C9orf152 | 0.72117283 | 0.50374775 | − 0.5176436 | 5.36E−17 | − 0.4220685 | 3.92E−20 | ||||||
| ALG1L | 0.48252392 | 0.29147766 | − 0.7272152 | 1.31E−15 | − 0.4049484 | 1.62E−18 | ||||||
| LYPLAL1 | 0.21600689 | 0.37575249 | 0.79870533 | 1.37E−15 | − 0.5716257 | 6.26E−39 | ||||||
| FAXDC2 | 0.18743077 | 0.27804419 | 0.56895638 | 2.06E−14 | − 0.5090998 | 6.27E−30 | ||||||
| GSTM2 | 0.1676375 | 0.25583059 | 0.60984384 | 1.08E−13 | − 0.37316 | 9.39E−16 | ||||||
| RPS6KA6 | 0.3918945 | 0.58429377 | 0.57622858 | 1.14E−13 | − 0.593005 | 1.79E−42 | ||||||
| GSTM1 | 0.18134566 | 0.36078245 | 0.99238695 | 3.75E−13 | − 0.5991552 | 1.53E−43 | ||||||
| ZNF471 | 0.07742318 | 0.15964683 | 1.04404648 | 4.11E−12 | − 0.4331758 | 3.12E−21 | ||||||
| ZNF501 | 0.21907069 | 0.39138671 | 0.83719832 | 1.18E−11 | − 0.5880791 | 1.24E−41 | ||||||
| HPDL | 0.07659738 | 0.21061474 | 1.45923942 | 5.54E−11 | − 0.3521578 | 4.35E−14 | ||||||
| EID3 | 0.09448771 | 0.27900888 | 1.5621124 | 1.44E−10 | − 0.3539739 | 3.16E−14 | ||||||
| PRAME | 0.71350801 | 0.48887503 | − 0.5454639 | 3.75E−09 | − 0.6966287 | 3.82E−64 | ||||||
| POU3F3 | 0.20637371 | 0.30865963 | 0.58075762 | 2.24E−08 | − 0.3212335 | 7.52E−12 | ||||||
| MPV17L | 0.06603454 | 0.13922797 | 1.07615617 | 5.38E−08 | − 0.3533641 | 3.52E−14 | ||||||
| NOVA1 | 0.18514835 | 0.29550643 | 0.67450785 | 3.74E−07 | − 0.3407751 | 3.10E−13 | ||||||
| TUSC1 | 0.08324606 | 0.18763643 | 1.17248603 | 0.00048328 | − 0.5222237 | 1.15E−31 | ||||||
| FOXG1 | 0.22293814 | 0.32155696 | 0.52843088 | 0.00791315 | − 0.4117017 | 3.83E−19 | ||||||
| CXCL1 | 0.14772043 | 0.22793677 | 0.62576431 | 0.01593495 | − 0.3218651 | 6.81E−12 | ||||||