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. 2021 Jul 10;19:299. doi: 10.1186/s12967-021-02964-6

Table 2.

Correlations of WT1 mRNA and ACE mRNA with demographic and clinical parameters within total sample, DN group and DM group, separately

mRNA Age BMI FBS HbA1c Urea S. Cr eGFR Alb/Cr
Total WT1 r 0.222 − 0.167 0.423 0.571 0.193 0.200 0.042 0.509
p 0.004 0.252 < 0.001  < 0.001 0.002 0.001 0.636 < 0.001
ACE r − 0.101 0.180 − 0.402 − 0.592 − 0.135 − 0.177 0.058 − 0.465
p 0.190 0.216 < 0.001 < 0.001 0.032 0.005 0.505 < 0.001
DN group WT1 r 0.161 − 0.207 0.270 0.341 0.020 0.221 − 0.201 0.602
p 0.239 0.565 0.006 < 0.001 0.845 0.025 0.326 < 0.001
ACE r − 0.110 0.250 − 0.340 − 0.445 − 0.021 − 0.159 0.273 − 0.474
p 0.424 0.486 0.001 < 0.001 0.836 0.110 0.177 < 0.001
DM group WT1 r 0.040 − 0.172 0.280 0.518 0.001 0.007 0.138 0.018
p 0.736 0.331 0.005 < 0.001 0.991 0.944 0.262 0.864
ACE r 0.050 0.154 − 0.372 − 0.685 0.064 − 0.025 0.040 − 0.234
p 0.670 0.386 < 0.001 < 0.001 0.526 0.803 0.747 0.020

BMI body mass index, FBS fasting blood glucose, S. Cr serum creatinine, eGFR estimated glomerular filtration rate, Alb/Cr urine albumin/creatinine ratio

r = correlation coefficient of spearman, p = p-value