Table 2.
Correlations of WT1 mRNA and ACE mRNA with demographic and clinical parameters within total sample, DN group and DM group, separately
mRNA | Age | BMI | FBS | HbA1c | Urea | S. Cr | eGFR | Alb/Cr | ||
---|---|---|---|---|---|---|---|---|---|---|
Total | WT1 | r | 0.222 | − 0.167 | 0.423 | 0.571 | 0.193 | 0.200 | 0.042 | 0.509 |
p | 0.004 | 0.252 | < 0.001 | < 0.001 | 0.002 | 0.001 | 0.636 | < 0.001 | ||
ACE | r | − 0.101 | 0.180 | − 0.402 | − 0.592 | − 0.135 | − 0.177 | 0.058 | − 0.465 | |
p | 0.190 | 0.216 | < 0.001 | < 0.001 | 0.032 | 0.005 | 0.505 | < 0.001 | ||
DN group | WT1 | r | 0.161 | − 0.207 | 0.270 | 0.341 | 0.020 | 0.221 | − 0.201 | 0.602 |
p | 0.239 | 0.565 | 0.006 | < 0.001 | 0.845 | 0.025 | 0.326 | < 0.001 | ||
ACE | r | − 0.110 | 0.250 | − 0.340 | − 0.445 | − 0.021 | − 0.159 | 0.273 | − 0.474 | |
p | 0.424 | 0.486 | 0.001 | < 0.001 | 0.836 | 0.110 | 0.177 | < 0.001 | ||
DM group | WT1 | r | 0.040 | − 0.172 | 0.280 | 0.518 | 0.001 | 0.007 | 0.138 | 0.018 |
p | 0.736 | 0.331 | 0.005 | < 0.001 | 0.991 | 0.944 | 0.262 | 0.864 | ||
ACE | r | 0.050 | 0.154 | − 0.372 | − 0.685 | 0.064 | − 0.025 | 0.040 | − 0.234 | |
p | 0.670 | 0.386 | < 0.001 | < 0.001 | 0.526 | 0.803 | 0.747 | 0.020 |
BMI body mass index, FBS fasting blood glucose, S. Cr serum creatinine, eGFR estimated glomerular filtration rate, Alb/Cr urine albumin/creatinine ratio
r = correlation coefficient of spearman, p = p-value