Table 3.
Stepwise multivariate linear regression analyses on the factors influencing WT1 mRNA and ACE mRNA
Predictor factorsa | Unstandardized coefficients | Standardized coefficients | t | p-value* | |
---|---|---|---|---|---|
B | SE | Beta | |||
Dependent variable: WT1 mRNA | |||||
Constant | − 0.024 | 0.197 | − 0.120 | 0.905 | |
HbA1c | 0.142 | 0.021 | 0.426 | 6.661 | < 0.001 |
S. Cr | 0.236 | 0.113 | 0.130 | 2.081 | 0.039 |
Alb/Cr ratio | 0.001 | < 0.001 | 0.322 | 4.832 | < 0.001 |
Dependent variable: ACE mRNA | |||||
Constant | 1.730 | 0.097 | 17.829 | < 0.001 | |
HbA1c | − 0.113 | 0.012 | − 0.502 | − 9.087 | < 0.001 |
Alb/Cr ratio | < 0.001 | < 0.001 | − 0.176 | − 3.190 | 0.002 |
FBS fasting blood glucose, S. Cr serum creatinine, Alb/Cr ratio urine albumin/creatinine ratio, SE standard error
aThe following independent variables were adopted for multivariate linear regression analysis of WT1 mRNA: age, FBS, HbA1c, urea, serum creatinine and urine Alb/Cr ratio
*p-value < 0.05 was considered statistically significant