Table 4.

The diagnostic accuracy of WT1 mRNA and 1/ACE mRNA for predicting incipient DN

Parameters	Threshold values	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	AUC (95% CI)	p value
WT1 mRNA	1.50	50.0	74.0	55.9	69.1	0.63 (0.55, 0.72)	0.003
$\frac{1}{\text{ACE}\text{mRNA}}$	1.15	65.2	61.0	52.4	72.6	0.62 (0.54, 0.71)	0.005

AUC area under the curve, PPV positive predictive value, NPV negative predictive value