Table 2.
Ten target genes were involved in the KEGG pathway, including CALM1, AP2M1, NDUFV1, ENO1, PFKM, ATP5B, ATP5C1, GPI, ME3, CDK5R1, which were mainly enriched in Alzheimer's disease, carbon metabolism, glycolysis/gluconeogenesis, and Huntington's disease. The bold label (ENO1, PFKM, ATP5B, ATP5C1, and GPI) meant these genes also belonged to the key hub genes
| Symbols | Full Names | Gene IDs |
|---|---|---|
| CALM1 | Calmodulin 1 | 801 |
| AP2M1 | Adaptor related protein complex 2 subunit mu 1 | 1173 |
| NDUFV1 | NADH:ubiquinone oxidoreductase core subunit V1 | 4723 |
| ENO1 | Enolase 1 | 2023 |
| PFKM | Phosphofructokinase, muscle | 5213 |
| ATP5B (ATP5F1B) | ATP synthase F1 subunit beta | 506 |
| ATP5C1 (ATP5F1C) | ATP synthase F1 subunit gamma | 509 |
| GPI | Glucose-6-phosphate isomerase | 2821 |
| ME3 | Malic enzyme 3 | 10,873 |
| CDK5R1 | Cyclin dependent kinase 5 regulatory subunit 1 | 8851 |