Table 1.
Comparison of intensity of staining between three groups for different biomarkers using Chi-square test
| Biomarkers | Intensity | Normal mucosa, n (%) | OSMF, n (%) | OSMF with dysplasia, n (%) | χ2 | P |
|---|---|---|---|---|---|---|
| E cadherin | No stain | 0 | 0 | 3 (15) | 15.100 | 0.02* |
| Weak | 0 | 2 (10) | 4 (20) | |||
| Moderate | 3 (15) | 7 (35) | 5 (25) | |||
| Strong | 17 (85) | 11 (55) | 8 (40) | |||
| Snail 1 | No stain | 4 (20) | 8 (40) | 7 (35) | 19.102 | 0.004* |
| Weak | 8 (40) | 0 | 0 | |||
| Moderate | 4 (20) | 6 (30) | 5 (25) | |||
| Strong | 4 (20) | 6 (30) | 8 (40) | |||
| Twist | No stain | 15 (75) | 8 (40) | 8 (40) | 14.561 | 0.02* |
| Weak | 5 (25) | 2 (10) | 3 (15) | |||
| Moderate | 0 | 2 (10) | 1 (5) | |||
| Strong | 0 | 8 (40) | 8 (40) |
*Significant statistically (the level of significance for all the inferential test was set at p less than 0.05), OSMF: Oral submucous fibrosis