Table 2.
Comparison of percentage staining of cells between the three groups for different biomarkers using Chi-square test
| Biomarkers | Percentage of staining cells | Normal mucosa, n (%) | OSMF, n (%) | OSMF with dysplasia, n (%) | χ2 | P |
|---|---|---|---|---|---|---|
| E-cadherin | No expression | 0 | 0 | 3 (15) | 15.350 | 0.04* |
| <25 | 0 | 1 (5) | 2 (10) | |||
| 25–50 | 2 (10) | 7 (35) | 6 (30) | |||
| 51–75 | 8 (40) | 3 (15) | 4 (20) | |||
| 76–100 | 10 (50) | 9 (45) | 5 (25) | |||
| Snail 1 | No expression | 4 (20) | 8 (40) | 7 (35) | 20.456 | 0.002* |
| <25 | 9 (45) | 1 (5) | 0 | |||
| 25–50 | 5 (25) | 4 (20) | 4 (20) | |||
| 51–75 | 2 (10) | 7 (35) | 9 (45) | |||
| 76–100 | 0 | 0 | 0 | |||
| Twist | No expression | 15 (75) | 8 (40) | 8 (40) | 16.078 | 0.01* |
| <25 | 4 (20) | 1 (5) | 3 (15) | |||
| 25–50 | 1 (5) | 6 (30) | 2 (10) | |||
| >50 | 0 | 5 (25) | 7 (35) |
*Significant statistically. OSMF: Oral submucous fibrosis