Table 1.

Summary of NU-0129 treatment-related adverse events in cynomolgus monkeys (A) and GBM patients (B).

A
Category	Term	animals affected
Investigations	Blue discoloration of tissues	all
Investigations	Injection site findings of acute perivascular hemorrhage	all
Vascular disorders	lower diastolic and mean arterial pressure lower systolic blood pressure	8 mg/kg group
B
		Grade
Category	Term	1	2	3	4	5	Patients affected
Blood and lymphatic system disorders	Anemia	1	0	0	0	0	1
Investigations	Alkaline phosphatase increased	1	0	0	0	0	1
Investigations	Lymphocyte count decreased	0	1	1	0	0	2
Investigations	White blood cell decreased	1	0	0	0	0	1
Metabolism and nutrition disorders	Hypophosphatemia	0	0	1	1	0	2
Vascular disorders	Hypertension	0	1	0	0	0	1
Total		3	2	2	1	0	8