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. 2021 Jun 18;131:16–40. doi: 10.1016/j.actbio.2021.06.023

Fig. 2.

Fig. 2

Structure of a typical lipid nanoparticle formulation. The cartoon scheme (left) highlights key components of a lipid nanoparticle with payload and how they contribute to its structure and function (above, right). A representative cryogenic transmission electron micrograph of LNPs with an mRNA cargo is shown on the bottom right, adapted with permission from Richner et al. 2017 [97].