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. Author manuscript; available in PMC: 2021 Oct 10.
Published in final edited form as: J Am Chem Soc. 2021 Feb 2;143(5):2194–2199. doi: 10.1021/jacs.0c12330

Figure 4.

Figure 4.

(a) Loss of mitochondria membrane potential by the JC-1 assay. Red channel indicates J-aggregate and green indicates monomer form of JC-1 molecules. (b) Release of cytochrome c (green) from mitochondria (red). (c) 1O2 generation by the SOSG assay (green). (d) Cell apoptosis visualized by annexin-V (green) and PI (red) staining. (e) ICD detected by CRT expression on the cell surface (green). Cell nuclei were stained by Hoechst 33342 (blue) in (d) and (e). MC38 cells were used, and all scale bars equal 20 μm.