General treatment algorithm for OCD of the talus. Dotted arrow indicates alternative treatment after initial failure. ACI = autologous chondrocyte implantation, CAM = controlled ankle motion, CT = computed tomography, H&P = history and physical examination, MACI = matrix-assisted autologous chondrocyte implantation, MRI = magnetic resonance imaging, and OAT = osteochondral autograft or allograft transplantation.