FIG. 8.

Multifunctional hydrogels for diabetic wounds with persistent infections: (a) a schematic diagram illustrating the injectable, self-healing, and adhesive hydrogel (FEMI) hydrogel for multidrug-resistant (MDR) bacteria-infected diabetic wound healing. After loading insulin and MnO₂ nanosheets, the hydrogel can regulate blood glucose and relieve oxidative stress of wounds.³⁰ Reproduced with permission from Wang et al., Nano Lett. 20(7), 5149–5158 (2020). Copyright 2020 American Chemical Society. (b) A preparation scheme of a yeast immobilized and copper nanoparticle incorporated wound dressing, the dressing can produce ethanol by consuming glucose, helping to control bacteria growth.¹⁵⁶ Reproduced with permission from Bhadauriya et al., ACS Appl. Bio Mater. 1(2), 246–258 (2018). Copyright 2018 American Chemical Society.