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. 2021 Jul 2;2021:1070365. doi: 10.1155/2021/1070365

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Copyright © 2021 Yuxia Wang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Restoration of FOXE1 reverses the effects of miR-330-5p on migration, invasion, and proliferation of TC. (a) qRT-PCR detection showed that FOXE1 levels were successfully enhanced by transfection with pc-FOXE1 in both TPC-1 and K-1 cells. (b) CCK-8 assays for the cell proliferation at the indicated time points (24, 48, and 72 h). (c) EdU assays for the cell proliferation. (d) Wound-healing and (e) Transwell assays for the migration and invasion abilities. (f) TPC-1 and K-1 cells were transfected with NC + pc-NC, miR-330-5p + pc-NC, or miR-330-5p inhibitor + pc-FOXE1. Values are mean ± SD. ^∗∗P < 0.01versus NC + pc-NC. ^#P < 0.05 and ^##P < 0.01versus miR-330-5p mimic + pc-NC.