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. 2021 Jul 2;2021:6663602. doi: 10.1155/2021/6663602

Table 2.

Herbal mixture for dysmenorrhea caused by EM treatment in the literature.

Herbal mixture sample/case number (n) Ingredients Control sample number (n) Total clinical effect rate Model used Therapeutic effects and actions Refs.
Shaofu Zhuyu decoction (SZD); n = 20 Xiao Hui Xiang, Gan Jiang, Yuan Hu, Mo Yao, Dang Gui, Chuan Xiong, Guan Gui, Mu Dan Gen, Pu Huang, Wu Ling Zhi Ibuprofen; n = 20 T: 90.00% versus 70.00% Human study Alleviating dysmenorrhea.
CA-125↓, PEG2↓
[23]
Wengjing decoction (WJD); n = 48 Wu Zhu Yu, Mai Dong, Dang Gui, Mu Dan Pi, Chuan Xiong, Ren Sheng, Gui Zhi, E Jiao, Bai Shao, Sheng Jiang, Ban Xia, Gan Cao Mifepristone; n = 48 T: 93.75% versus 79.17% Human study Alleviating dysmenorrhea.
CD4+↓, CD4+/CD8+↓, IL-4↓, IL-10↓
[26]
Xuefu Zhuyu decoction (XZD); n = 60 Dang Gui, Sheng Di Huang, Tao Ren, Hong Hua, Zhi Qiao, Chi Shao, Chai Hu , Gan Cao, Jie Geng, Chuan Xiong, Niu Xi Mifepristone; n = 60 T: 90.0% versus 73.3% Human study Alleviating dysmenorrhea.
Reducing VAS scores.
[30]
Danggui Sini decoction (DSD); n = 37 Dang Gui, Gui Zhi, Shao Yao, Xi Xin, Tong Cao, Zhi Gan Cao, Da Zao Progesterone; n = 37 D: 89.19% versus 67.57% Human study Alleviating dysmenorrhea. [34]
Danggui Shaoyao Powder (DSP); n = 40 Dang Gui, Shao Yao, Chuan Xiong, Fu Ling, Ze Xie, Bai Zhu Progesterone; n = 40 T: 97.5% versus 82.5% Human study Alleviating dysmenorrhea.
Reducing VAS scores. PEG2↓, P↓
[35]

Note: T (Total effect rate) = number of effective cases/total number of cases; where effective case refers to the patients or animal models whose signs and symptoms were improved after treatment. D: dysmenorrhea alleviation rate.