Fig. 3.

Kinetics of blood cell counts and factors related to neutrophil activation during an HAE attack (single patient). a Kinetics of WBC, thrombocyte, lymphocyte, and neutrophil-, eosinophil-, and basophil-granulocyte count during an HAE attack of a C1-INH-HAE patient (solid line with closed dots), and an age- and gender-matched healthy control (dashed line with open dots). Severity levels of angioedema symptoms were assessed by the patient in on a VAS scale (0–100 mm). Symptom-free periods are marked with green, prodromal phases with yellow, and attack phases with orange. The dotted lines indicate normal ranges. b Kinetics of neutrophil-related factors of the same patient and control