Table 2.
Peripheral blood cell type count in samples obtained from healthy subjects and C1-INH-HAE patients during symptom-free periods
| Healthy controls (n = 79) | C1-INH-HAE symptom-free period (n = 77) | P value | Normal range | |
|---|---|---|---|---|
| White blood cell (109/L) | 6.38 (5.1–7.4) | 7.25 (6.3–8.5) | 0.0013 | 4.00–10.00 |
| Lymphocyte (109/L) | 1.92 (1.5–2.3) | 2.14 (1.9–2.6) | 0.0010 | 1.00–4.00 |
| Thrombocyte (109/L) | 244.5 (215.3–286.8) | 262.5 (224–306) | nsa | 150–400 |
| Monocyte (109/L) | 0.35 (0.28–0.42) | 0.35 (0.3–0.43) | ns | 0.15–0.90 |
| Neutrophil granulocyte (109/L) | 3.78 (2.82–4.82) | 4.34 (3.57–5.5) | 0.0029 | 2.00–6.90 |
| Eosinophil granulocyte (109/L) | 0.125 (0.04–0.18) | 0.13 (0.08–0.16) | ns | 0.03–0.50 |
| Basophil granulocyte (109/L) | 0.03 (0.01–0.04) | 0.04 (0.02–0.05) | 0.0123 | 0.01–0.20 |
Ns non-significant
Values are medians (25–75% percentile). P values were calculated with Mann–Whitney test in most cases
aUnpaired t test