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. 2021 Jul 10;7:178. doi: 10.1038/s41420-021-00560-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A Heatmap of 1031 upregulated lncRNAs in 371 HCC tissues compared with 50 normal tissues B Volcano plot showed the distribution of the seven-lncRNA differential expression, which positively correlated with CSN5 co-expression between HCC and adjacent normal tissues (No Diff no difference, UP upregulation, Down downregulation). C Heatmap for the seven-lncRNA expression profiles. D Table presented the relative fold changes of lncRNAs in HCC, compared to normal samples, and the correlation coefficients with CSN5 levels.