Table 1.
Characteristics at visit 1 in discovery sample and replication sample by diagnostic group.
| Study sample | Phenotypes | Diagnostic groups mean (s.d.) or percentage (%) | Group difference | ||
|---|---|---|---|---|---|
| Affective | Psychotic | Controls | P value | ||
| Discovery sample | Age | 44.6 (13.4) | 41.1 (12.1) | 37.1 (15.6) | – |
| Females | 49.8 % | 39.6 % | 58.1 % | – | |
| TMT-B | 83.9 (42.6) | 92.3 (41.3) | 59.4 (25.1) | <2 × 10−16 | |
| VDS-B | 6.2 (2.1) | 5.5 (2.0) | 7.3 (2.9) | <2 × 10−16 | |
| Replication sample | Age | 37.6 (13.4) | 38.4 (11.3) | 34.1 (12.6) | – |
| Females | 63.9 % | 44.6 % | 63.0 % | – | |
| TMT-B | 57.7 (23.9) | 73.6 (30.9) | 48.8 (18.6) | <2 × 10−16 | |
| LNST | 15.7 (3.3) | 13.4 (3.5) | 16.8 (3.2) | <2 × 10−16 | |
The proportion of females (%), means of age (years), TMT-B, and VDS-B/LNST with standard deviation (s.d.).
We tested for differences in means between the diagnostic groups for lgTMT-B and VDS-B. Results are only displayed for visit 1 as results for the other visits proved to be similar.